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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
Postnatal

121 matching records from 121 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Trp63  transformation related protein 63   (Synonyms: deltaNp63, KET protein, p51/p63, p63, p73L, TAp63, Trp53rp1)
Results  Reference
1*J:231231 Abby E, Tourpin S, Ribeiro J, Daniel K, Messiaen S, Moison D, Guerquin J, Gaillard JC, Armengaud J, Langa F, Toth A, Martini E, Livera G, Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. Nat Commun. 2016;7:10324
1J:177655 Arnold K, Sarkar A, Yram MA, Polo JM, Bronson R, Sengupta S, Seandel M, Geijsen N, Hochedlinger K, Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice. Cell Stem Cell. 2011 Oct 4;9(4):317-29
1J:276773 Beeler JS, Marshall CB, Gonzalez-Ericsson PI, Shaver TM, Santos Guasch GL, Lea ST, Johnson KN, Jin H, Venters BJ, Sanders ME, Pietenpol JA, p73 regulates epidermal wound healing and induced keratinocyte programming. PLoS One. 2019;14(6):e0218458
1J:276488 Bilodeau M, Shojaie S, Ackerley C, Post M, Rossant J, Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential. Stem Cell Reports. 2014 Oct 14;3(4):634-49
1J:254216 Bin BH, Bhin J, Takaishi M, Toyoshima KE, Kawamata S, Ito K, Hara T, Watanabe T, Irie T, Takagishi T, Lee SH, Jung HS, Rho S, Seo J, Choi DH, Hwang D, Koseki H, Ohara O, Sano S, Tsuji T, Mishima K, Fukada T, Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10-p63 axis in epithelial homeostasis. Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12243-12248
1J:105284 Birger Y, Davis J, Furusawa T, Rand E, Piatigorsky J, Bustin M, A role for chromosomal protein HMGN1 in corneal maturation. Differentiation. 2006 Feb;74(1):19-29
1J:114702 Blanpain C, Lowry WE, Pasolli HA, Fuchs E, Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev. 2006 Nov 1;20(21):3022-35
1J:205657 Boase NA, Rychkov GY, Townley SL, Dinudom A, Candi E, Voss AK, Tsoutsman T, Semsarian C, Melino G, Koentgen F, Cook DI, Kumar S, Respiratory distress and perinatal lethality in Nedd4-2-deficient mice. Nat Commun. 2011;2:287
1J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801
1J:244068 Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, Ludtke TH, Trowe MO, Kispert A, A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017 Aug;13(8):e1006951
1J:185338 Boucherat O, Chakir J, Jeannotte L, The loss of Hoxa5 function promotes Notch-dependent goblet cell metaplasia in lung airways. Biol Open. 2012;q:677-691
1J:258787 Bresson L, Faraldo MM, Di-Cicco A, Quintanilla M, Glukhova MA, Deugnier MA, Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/beta-catenin signaling. Development. 2018 Feb 21;145(4):dev160382
1J:335426 Butera A, Agostini M, Cassandri M, De Nicola F, Fanciulli M, D'Ambrosio L, Falasca L, Nardacci R, Wang L, Piacentini M, Knight RA, Jia W, Sun Q, Shi Y, Wang Y, Candi E, Melino G, ZFP750 affects the cutaneous barrier through regulating lipid metabolism. Sci Adv. 2023 Apr 28;9(17):eadg5423
1J:316303 Camacho Leal MDP, Costamagna A, Tassone B, Saoncella S, Simoni M, Natalini D, Dadone A, Sciortino M, Turco E, Defilippi P, Calautti E, Cabodi S, Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation. Cell Commun Signal. 2018 Nov 3;16(1):73
1J:196968 Campolo F, Gori M, Favaro R, Nicolis S, Pellegrini M, Botti F, Rossi P, Jannini EA, Dolci S, Essential role of Sox2 for the establishment and maintenance of the germ cell line. Stem Cells. 2013 Jul;31(7):1408-21
1J:199784 Cancino GI, Yiu AP, Fatt MP, Dugani CB, Flores ER, Frankland PW, Josselyn SA, Miller FD, Kaplan DR, p63 Regulates Adult Neural Precursor and Newly Born Neuron Survival to Control Hippocampal-Dependent Behavior. J Neurosci. 2013 Jul 31;33(31):12569-85
1*J:228706 Chandramouli A, Simundza J, Pinderhughes A, Hiremath M, Droguett G, Frendewey D, Cowin P, Ltbp1L is focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution. Breast Cancer Res. 2013;15(6):R111
1J:177389 Chikh A, Matin RN, Senatore V, Hufbauer M, Lavery D, Raimondi C, Ostano P, Mello-Grand M, Ghimenti C, Bahta A, Khalaf S, Akgul B, Braun KM, Chiorino G, Philpott MP, Harwood CA, Bergamaschi D, iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia. EMBO J. 2011;30(20):4261-73
1J:309371 Chilukuri RV, Patel VK, Martinez M, Guyden JC, Samms MD, The Antigenic Determinant That Defines Thymic Nurse Cells Is Expressed by Thymic Epithelial Progenitor Cells. Front Cell Dev Biol. 2014 Apr 28;2(13)
1J:130204 Cook C, Vezina CM, Allgeier SH, Shaw A, Yu M, Peterson RE, Bushman W, Noggin is required for normal lobe patterning and ductal budding in the mouse prostate. Dev Biol. 2007 Dec 1;312(1):217-30
1J:171221 Croyle MJ, Lehman JM, O'Connor AK, Wong SY, Malarkey EB, Iribarne D, Dowdle WE, Schoeb TR, Verney ZM, Athar M, Michaud EJ, Reiter JF, Yoder BK, Role of epidermal primary cilia in the homeostasis of skin and hair follicles. Development. 2011 May;138(9):1675-85
1J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227
1J:95347 Daniely Y, Liao G, Dixon D, Linnoila RI, Lori A, Randell SH, Oren M, Jetten AM, Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am J Physiol Cell Physiol. 2004 Jul;287(1):C171-81
1J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543
1J:252728 Elo T, Lindfors PH, Lan Q, Voutilainen M, Trela E, Ohlsson C, Huh SH, Ornitz DM, Poutanen M, Howard BA, Mikkola ML, Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty. Sci Rep. 2017 Jul 11;7(1):5049
1J:195087 Francis JC, Thomsen MK, Taketo MM, Swain A, beta-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma. PLoS Genet. 2013 Jan;9(1):e1003180
1*J:148798 Furusawa T, Ko JH, Birger Y, Bustin M, Expression of nucleosomal protein HMGN1 in the cycling mouse hair follicle. Gene Expr Patterns. 2009 Jun;9(5):289-95
1J:204539 Gandhi D, Molotkov A, Batourina E, Schneider K, Dan H, Reiley M, Laufer E, Metzger D, Liang F, Liao Y, Sun TT, Aronow B, Rosen R, Mauney J, Adam R, Rosselot C, Van Batavia J, McMahon A, McMahon J, Guo JJ, Mendelsohn C, Retinoid signaling in progenitors controls specification and regeneration of the urothelium. Dev Cell. 2013 Sep 16;26(5):469-82
1*J:221639 Georgas KM, Armstrong J, Keast JR, Larkins CE, McHugh KM, Southard-Smith EM, Cohn MJ, Batourina E, Dan H, Schneider K, Buehler DP, Wiese CB, Brennan J, Davies JA, Harding SD, Baldock RA, Little MH, Vezina CM, Mendelsohn C, An illustrated anatomical ontology of the developing mouse lower urogenital tract. Development. 2015 May 15;142(10):1893-908
1J:289854 Haglin S, Berghard A, Bohm S, Increased Retinoic Acid Catabolism in Olfactory Sensory Neurons Activates Dormant Tissue-Specific Stem Cells and Accelerates Age-Related Metaplasia. J Neurosci. 2020 May 20;40(21):4116-4129
1J:112460 Hatsell SJ, Cowin P, Gli3-mediated repression of Hedgehog targets is required for normal mammary development. Development. 2006 Sep;133(18):3661-70
1J:170248 Hernandez-Acosta NC, Cabrera-Socorro A, Morlans MP, Delgado FJ, Suarez-Sola ML, Sottocornola R, Lu X, Gonzalez-Gomez M, Meyer G, Dynamic expression of the p53 family members p63 and p73 in the mouse and human telencephalon during development and in adulthood. Brain Res. 2011 Feb 4;1372:29-40
1J:240020 Herriges JC, Verheyden JM, Zhang Z, Sui P, Zhang Y, Anderson MJ, Swing DA, Zhang Y, Lewandoski M, Sun X, FGF-Regulated ETV Transcription Factors Control FGF-SHH Feedback Loop in Lung Branching. Dev Cell. 2015 Nov 09;35(3):322-32
1*J:243650 Herriges MJ, Tischfield DJ, Cui Z, Morley MP, Han Y, Babu A, Li S, Lu M, Cendan I, Garcia BA, Anderson SA, Morrisey EE, The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. Genes Dev. 2017 May 01;31(9):889-903
1J:300508 Hilliard SA, Li Y, Dixon A, El-Dahr SS, Mdm4 controls ureteric bud branching via regulation of p53 activity. Mech Dev. 2020 Sep;163:103616
1J:203056 Hines EA, Jones MK, Verheyden JM, Harvey JF, Sun X, Establishment of smooth muscle and cartilage juxtaposition in the developing mouse upper airways. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19444-9
1J:248683 Hirayama T, Asano Y, Iida H, Watanabe T, Nakamura T, Goitsuka R, Meis1 is required for the maintenance of postnatal thymic epithelial cells. PLoS One. 2014;9(3):e89885
1J:315539 Hu L, Liu J, Li Z, Ozturk F, Gurumurthy C, Romano RA, Sinha S, Nawshad A, TGFbeta3 regulates periderm removal through DeltaNp63 in the developing palate. J Cell Physiol. 2015 Jun;230(6):1212-25
1J:333827 Huang C, Zhao S, Yang Y, Guo T, Ke H, Mi X, Qin Y, Chen ZJ, Zhao S, TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis. J Clin Invest. 2023 Mar 1;133(5)
1J:252735 Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J, Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. 2017 Oct 26;550(7677):529-533
1*J:169680 Karni-Schmidt O, Castillo-Martin M, Shen TH, Gladoun N, Domingo-Domenech J, Sanchez-Carbayo M, Li Y, Lowe S, Prives C, Cordon-Cardo C, Distinct Expression Profiles of p63 Variants during Urothelial Development and Bladder Cancer Progression. Am J Pathol. 2011 Mar;178(3):1350-60
1*J:207607 Keil KP, Abler LL, Mehta V, Altmann HM, Laporta J, Plisch EH, Suresh M, Hernandez LL, Vezina CM, DNA methylation of E-cadherin is a priming mechanism for prostate development. Dev Biol. 2014 Mar 15;387(2):142-53
1J:300306 Kim E, Choi S, Kang B, Kong J, Kim Y, Yoon WH, Lee HR, Kim S, Kim HM, Lee H, Yang C, Lee YJ, Kang M, Roh TY, Jung S, Kim S, Ku JH, Shin K, Creation of bladder assembloids mimicking tissue regeneration and cancer. Nature. 2020 Dec;588(7839):664-669
1J:282804 Kim HT, Yin W, Nakamichi Y, Panza P, Grohmann B, Buettner C, Guenther S, Ruppert C, Kobayashi Y, Guenther A, Stainier DYR, WNT/RYK signaling restricts goblet cell differentiation during lung development and repair. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25697-25706
1J:327072 Kim WK, Olson AW, Mi J, Wang J, Lee DH, Le V, Hiroto A, Aldahl J, Nenninger CH, Buckley AJ, Cardiff R, You S, Sun Z, Aberrant androgen action in prostatic progenitor cells induces oncogenesis and tumor development through IGF1 and Wnt axes. Nat Commun. 2022 Jul 28;13(1):4364
1J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9
1J:347128 Kumar N, Prakash PG, Wentland C, Kurian SM, Jethva G, Brinkmann V, Mollenkopf HJ, Krammer T, Toussaint C, Saliba AE, Biebl M, Jurgensen C, Wiedenmann B, Meyer TF, Gurumurthy RK, Chumduri C, Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis. Nat Commun. 2024 Apr 9;15(1):3064
1*J:94980 Kurata S, Okuyama T, Osada M, Watanabe T, Tomimori Y, Sato S, Iwai A, Tsuji T, Ikawa Y, Katoh I, p51/p63 Controls subunit alpha3 of the major epidermis integrin anchoring the stem cells to the niche. J Biol Chem. 2004 Nov 26;279(48):50069-77
1*J:100707 Kurita T, Cunha GR, Robboy SJ, Mills AA, Medina RT, Differential expression of p63 isoforms in female reproductive organs. Mech Dev. 2005 Sep;122(9):1043-55
1J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522
1*J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735
1*J:108240 Kusakabe T, Hoshi N, Kimura S, Origin of the ultimobranchial body cyst: T/ebp/Nkx2.1 expression is required for development and fusion of the ultimobranchial body to the thyroid. Dev Dyn. 2006 May;235(5):1300-9
1J:107400 Laurikkala J, Mikkola ML, James M, Tummers M, Mills AA, Thesleff I, p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development. 2006 Apr;133(8):1553-63
1J:300878 Lena AM, Rossi V, Osterburg S, Smirnov A, Osterburg C, Tuppi M, Cappello A, Amelio I, Dotsch V, De Felici M, Klinger FG, Annicchiarico-Petruzzelli M, Valensise H, Melino G, Candi E, The p63 C-terminus is essential for murine oocyte integrity. Nat Commun. 2021 Jan 15;12(1):383
1J:162871 Li A, Xing Y, Chan B, Heisterkamp N, Groffen J, Borok Z, Minoo P, Li C, Cell type-specific expression of adenomatous polyposis coli in lung development, injury, and repair. Dev Dyn. 2010 Aug;239(8):2288-97
1J:191599 Li J, Jiang TX, Hughes MW, Wu P, Widelitz RB, Fan G, Chuong CM, Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. J Invest Dermatol. 2012 Dec;132(12):2681-90
1J:264609 Li J, Yuan Y, He J, Feng J, Han X, Jing J, Ho TV, Xu J, Chai Y, Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion. Dev Biol. 2018 Sep 1;441(1):191-203
1*J:171626 Li S, Xiang M, Foxn4 influences alveologenesis during lung development. Dev Dyn. 2011 Jun;240(6):1512-7
1J:316189 Lin C, Hindes A, Burns CJ, Koppel AC, Kiss A, Yin Y, Ma L, Blumenberg M, Khnykin D, Jahnsen FL, Crosby SD, Ramanan N, Efimova T, Serum response factor controls transcriptional network regulating epidermal function and hair follicle morphogenesis. J Invest Dermatol. 2013 Mar;133(3):608-617
1J:194053 Liu B, Liu YF, Du YR, Mardaryev AN, Yang W, Chen H, Xu ZM, Xu CQ, Zhang XR, Botchkarev VA, Zhang Y, Xu GL, Cbx4 regulates the proliferation of thymic epithelial cells and thymus function. Development. 2013 Feb;140(4):780-8
1J:281366 Liu C, Tate T, Batourina E, Truschel ST, Potter S, Adam M, Xiang T, Picard M, Reiley M, Schneider K, Tamargo M, Lu C, Chen X, He J, Kim H, Mendelsohn CL, Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells. Nat Commun. 2019 Oct 9;10(1):4589
1J:202355 Liu HX, Ermilov A, Grachtchouk M, Li L, Gumucio DL, Dlugosz AA, Mistretta CM, Multiple Shh signaling centers participate in fungiform papilla and taste bud formation and maintenance. Dev Biol. 2013 Oct 1;382(1):82-97
1J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790
1J:274694 Lodge EJ, Santambrogio A, Russell JP, Xekouki P, Jacques TS, Johnson RL, Thavaraj S, Bornstein SR, Andoniadou CL, Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade. Elife. 2019 Mar 26;8:e43996
1J:154022 Lopez RG, Garcia-Silva S, Moore SJ, Bereshchenko O, Martinez-Cruz AB, Ermakova O, Kurz E, Paramio JM, Nerlov C, C/EBPalpha and beta couple interfollicular keratinocyte proliferation arrest to commitment and terminal differentiation. Nat Cell Biol. 2009 Oct;11(10):1181-90
1J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82
1J:119922 Mailleux AA, Overholtzer M, Schmelzle T, Bouillet P, Strasser A, Brugge JS, BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms. Dev Cell. 2007 Feb;12(2):221-34
1J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68
1J:185038 Martinez P, Flores JM, Blasco MA, 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response. J Cell Biol. 2012 Apr 16;197(2):283-300
1J:291294 McAuley E, Moline D, VanOpstall C, Lamperis S, Brown R, Vander Griend DJ, Sox2 Expression Marks Castration-Resistant Progenitor Cells in the Adult Murine Prostate. Stem Cells. 2019 May;37(5):690-700
1J:298674 Mevel R, Steiner I, Mason S, Galbraith LC, Patel R, Fadlullah MZ, Ahmad I, Leung HY, Oliveira P, Blyth K, Baena E, Lacaud G, RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development. Elife. 2020 Oct 7;9:e60225
1J:161749 Mill P, Lee AW, Fukata Y, Tsutsumi R, Fukata M, Keighren M, Porter RM, McKie L, Smyth I, Jackson IJ, Palmitoylation regulates epidermal homeostasis and hair follicle differentiation. PLoS Genet. 2009 Nov;5(11):e1000748
1J:306379 Mohad V, Lungova V, Verheyden J, Thibeault SL, Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis. Dev Biol. 2021 May;473:33-49
1J:238903 Mori M, Mahoney JE, Stupnikov MR, Paez-Cortez JR, Szymaniak AD, Varelas X, Herrick DB, Schwob J, Zhang H, Cardoso WV, Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors. Development. 2015 Jan 15;142(2):258-67
1J:173864 Murashima A, Miyagawa S, Ogino Y, Nishida-Fukuda H, Araki K, Matsumoto T, Kaneko T, Yoshinaga K, Yamamura K, Kurita T, Kato S, Moon AM, Yamada G, Essential roles of androgen signaling in Wolffian duct stabilization and epididymal cell differentiation. Endocrinology. 2011 Apr;152(4):1640-51
1J:214297 Myers M, Morgan FH, Liew SH, Zerafa N, Gamage TU, Sarraj M, Cook M, Kapic I, Sutherland A, Scott CL, Strasser A, Findlay JK, Kerr JB, Hutt KJ, PUMA regulates germ cell loss and primordial follicle endowment in mice. Reproduction. 2014 Aug;148(2):211-9
1J:182928 Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA, Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators. J Cell Sci. 2010 Oct 15;123(Pt 20):3566-75
1J:315114 Nagosa S, Leesch F, Putin D, Bhattacharya S, Altshuler A, Serror L, Amitai-Lange A, Nasser W, Aberdam E, Rouleau M, Tattikota SG, Poy MN, Aberdam D, Shalom-Feuerstein R, microRNA-184 Induces a Commitment Switch to Epidermal Differentiation. Stem Cell Reports. 2017 Dec 12;9(6):1991-2004
1J:220954 Nakamura T, Ohtsuka T, Sekiyama E, Cooper LJ, Kokubu H, Fullwood NJ, Barrandon Y, Kageyama R, Kinoshita S, Hes1 regulates corneal development and the function of corneal epithelial stem/progenitor cells. Stem Cells. 2008 May;26(5):1265-74
1J:124280 Nieuwenhuis E, Barnfield PC, Makino S, Hui CC, Epidermal hyperplasia and expansion of the interfollicular stem cell compartment in mutant mice with a C-terminal truncation of Patched1. Dev Biol. 2007 Aug 15;308(2):547-60
1J:207286 Nowak JA, Polak L, Pasolli HA, Fuchs E, Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell. 2008 Jul 3;3(1):33-43
1*J:197594 Okubo T, Clark C, Hogan BL, Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate. Stem Cells. 2009 Feb;27(2):442-50
1J:173538 Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE, {Delta}Np63 regulates stem cell dynamics in the Mammalian olfactory epithelium. J Neurosci. 2011 Jun 15;31(24):8748-59
1*J:197339 Pignon JC, Grisanzio C, Geng Y, Song J, Shivdasani RA, Signoretti S, p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8105-10
1*J:326663 Qasrawi F, Meuser M, Lehnhoff F, Schulte M, Kispert A, S100A1 expression characterizes terminally differentiated superficial cells in the urothelium of the murine bladder and ureter. Histochem Cell Biol. 2022 Jun 1;
1J:149564 Que J, Luo X, Schwartz RJ, Hogan BL, Multiple roles for Sox2 in the developing and adult mouse trachea. Development. 2009 Jun;136(11):1899-907
1J:122531 Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan BL, Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development. 2007 Jul;134(13):2521-31
1J:219571 Rajaram RD, Buric D, Caikovski M, Ayyanan A, Rougemont J, Shan J, Vainio SJ, Yalcin-Ozuysal O, Brisken C, Progesterone and Wnt4 control mammary stem cells via myoepithelial crosstalk. EMBO J. 2015 Mar 4;34(5):641-52
1J:226044 Riemondy K, Wang XJ, Torchia EC, Roop DR, Yi R, MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells. Elife. 2015;4
1*J:138613 Rock JR, Futtner CR, Harfe BD, The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol. 2008 Sep 1;321(1):141-9
1J:166768 Rodriguez P, Da Silva S, Oxburgh L, Wang F, Hogan BL, Que J, BMP signaling in the development of the mouse esophagus and forestomach. Development. 2010 Dec;137(24):4171-6
1J:291600 Rodriguez-Seguel E, Villamayor L, Arroyo N, De Andres MP, Real FX, Martin F, Cano DA, Rojas A, Loss of GATA4 causes ectopic pancreas in the stomach. J Pathol. 2020 Apr;250(4):362-373
1J:149319 Romano RA, Ortt K, Birkaya B, Smalley K, Sinha S, An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate. PLoS One. 2009;4(5):e5623
1J:168262 Romano RA, Smalley K, Liu S, Sinha S, Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing DeltaNp63alpha. Development. 2010 May;137(9):1431-9
1J:254700 Seo S, Chen L, Liu W, Zhao D, Schultz KM, Sasman A, Liu T, Zhang HF, Gage PJ, Kume T, Foxc1 and Foxc2 in the Neural Crest Are Required for Ocular Anterior Segment Development. Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3):1368-1377
1J:297664 Simonson L, Vold S, Mowers C, Massey RJ, Ong IM, Longley BJ, Chang H, Keratin 13 deficiency causes white sponge nevus in mice. Dev Biol. 2020 Dec 1;468(1-2):146-153
1J:203426 Souquet B, Abby E, Herve R, Finsterbusch F, Tourpin S, Le Bouffant R, Duquenne C, Messiaen S, Martini E, Bernardino-Sgherri J, Toth A, Habert R, Livera G, MEIOB targets single-strand DNA and is necessary for meiotic recombination. PLoS Genet. 2013;9(9):e1003784
1J:322612 Spina E, Simundza J, Incassati A, Chandramouli A, Kugler MC, Lin Z, Khodadadi-Jamayran A, Watson CJ, Cowin P, Gpr125 is a unifying hallmark of multiple mammary progenitors coupled to tumor latency. Nat Commun. 2022 Mar 17;13(1):1421
1J:319645 Stefanski HE, Xing Y, Nicholls J, Jonart L, Goren E, Taylor PA, Mills AA, Riddle M, McGrath J, Tolar J, Hollander GA, Blazar BR, P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss. PLoS One. 2022;17(1):e0261770
1J:151638 Su X, Paris M, Gi YJ, Tsai KY, Cho MS, Lin YL, Biernaskie JA, Sinha S, Prives C, Pevny LH, Miller FD, Flores ER, TAp63 prevents premature aging by promoting adult stem cell maintenance. Cell Stem Cell. 2009 Jul 2;5(1):64-75
1J:212275 Sun P, Watanabe K, Fallahi M, Lee B, Afetian ME, Rheaume C, Wu D, Horsley V, Dai X, Pygo2 regulates beta-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10215-20
1J:215310 Sun W, Wilhelmina Aalders T, Oosterwijk E, Identification of potential bladder progenitor cells in the trigone. Dev Biol. 2014 Sep 1;393(1):84-92
1J:115581 Tian J, Mahmood R, Hnasko R, Locker J, Loss of Nkx2.8 deregulates progenitor cells in the large airways and leads to dysplasia. Cancer Res. 2006 Nov 1;66(21):10399-407
1J:167962 Tiozzo C, De Langhe S, Yu M, Londhe VA, Carraro G, Li M, Li C, Xing Y, Anderson S, Borok Z, Bellusci S, Minoo P, Deletion of Pten expands lung epithelial progenitor pools and confers resistance to airway injury. Am J Respir Crit Care Med. 2009 Oct 15;180(8):701-12
1J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63
1J:232924 Vaithiyanathan K, Liew SH, Zerafa N, Gamage T, Cook M, O'Reilly LA, Bouillet P, Scott CL, Strasser A, Findlay JK, Hutt KJ, BCL2-modifying factor promotes germ cell loss during murine oogenesis. Reproduction. 2016 May;151(5):553-62
1*J:294158 Vernersson Lindahl E, Garcia EL, Mills AA, An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. Am J Med Genet A. 2013 Aug;161A(8):1961-71
1J:173368 Wang X, Ouyang H, Yamamoto Y, Kumar PA, Wei TS, Dagher R, Vincent M, Lu X, Bellizzi AM, Ho KY, Crum CP, Xian W, McKeon F, Residual Embryonic Cells as Precursors of a Barrett's-like Metaplasia. Cell. 2011 Jun 24;145(7):1023-35
1J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26
1J:259982 Weng PL, Vinjamuri M, Ovitt CE, Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium. Sci Rep. 2016 Dec 2;6:38199
1J:93433 Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ, The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc Natl Acad Sci U S A. 2004 Oct 28;101(39):14114-9
1J:175387 Wu X, Xu K, Zhang L, Deng Y, Lee P, Shapiro E, Monaco M, Makarenkova HP, Li J, Lepor H, Grishina I, Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism. Dev Biol. 2011 Aug 15;356(2):337-49
1J:242196 Xu M, Horrell J, Snitow M, Cui J, Gochnauer H, Syrett CM, Kallish S, Seykora JT, Liu F, Gaillard D, Katz JP, Kaestner KH, Levin B, Mansfield C, Douglas JE, Cowart BJ, Tordoff M, Liu F, Zhu X, Barlow LA, Rubin AI, McGrath JA, Morrisey EE, Chu EY, Millar SE, WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation. Nat Commun. 2017 Jun 07;8:15397
1J:170443 Yi R, Poy MN, Stoffel M, Fuchs E, A skin microRNA promotes differentiation by repressing 'stemness'. Nature. 2008 Mar 13;452(7184):225-9
1J:321577 Yin W, Liontos A, Koepke J, Ghoul M, Mazzocchi L, Liu X, Lu C, Wu H, Fysikopoulos A, Sountoulidis A, Seeger W, Ruppert C, Gunther A, Stainier DYR, Samakovlis C, An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea. Development. 2022 Feb 1;149(3):dev199804
1J:169106 Zhang H, Pasolli HA, Fuchs E, Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2270-5
1*J:314587 Zhang S, Dai H, Li W, Wang R, Wu H, Shen M, Hu Y, Xie L, Xing Y, TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway. Cell Death Dis. 2021 Nov 16;12(12):1086
1J:159631 Zhang Y, Call MK, Yeh LK, Liu H, Kochel T, Wang IJ, Chu PH, Taketo MM, Jester JV, Kao WW, Liu CY, Aberrant expression of a beta-catenin gain-of-function mutant induces hyperplastic transformation in the mouse cornea. J Cell Sci. 2010 Apr 15;123(Pt 8):1285-94
1*J:317247 Zhao Q, Liu S, Zhang H, Li N, Wang X, Cao Y, Ning L, Duan E, Xia G, Spatiotemporal Expression of p63 in Mouse Epidermal Commitment. Int J Mol Sci. 2015 Dec 10;16(12):29542-53
1J:330195 Zhou Y, Yang Y, Guo L, Qian J, Ge J, Sinner D, Ding H, Califano A, Cardoso WV, Airway basal cells show regionally distinct potential to undergo metaplastic differentiation. Elife. 2022 Sep 30;11:e80083
1J:193135 Zong Y, Huang J, Sankarasharma D, Morikawa T, Fukayama M, Epstein JI, Chada KK, Witte ON, Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling. Proc Natl Acad Sci U S A. 2012 Dec 11;109(50):E3395-404

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